psa bounce after 9 months – All PSA after Brachytherapy?? messages

The pattern of the drop in PSA after radiation therapy is also different from after surgery. PSA levels after radiation tend to drop slowly, and might not reach their lowest level until 2 years or more after treatment. Doctors tend to follow the PSA levels every few months to look for trends.

8.11.2006 · So what should you do if have a rise in your PSA level after radiation? ”You have to get a few readings over the next year,” Horwitz says, adding that most doctors recommend screening every three months or so. ”But try to relax and realize that it’s OK, that this happens, and that a bounce does not mean your cancer has recurred,” he says.

I thought your father had surgery first, then radiation. If so, there is typically no radiation bounce when radiation is used as a secondary treatment. I had salvage radiation, and mine failed after 9 months. If your father only had radiation, as a primary treatment, there is typically a bounce at some point. Perhaps you could refresh our memory.

Experiencing a PSA bounce was associated with improved biochemical disease-free survival. A PSA bounce occurred sooner after radiotherapy than a recurrence of prostate cancer. In total, 33% of patients experienced at least one PSA bounce. A temporary rise in prostate-specific antigen (PSA) scores

Checking PSA levels every three to six months after radiotherapy, they found about 12% of the 964 patients had such a PSA bounce. Although Pisters worried that a PSA bounce meant the cancer was more likely to recur, he found just the opposite.

Objectives: The purpose of this study was to find out the frequency of PSA bouncing and the factors effecting PSA bounce after external beam radiation treatment (EBRT) with or without hormonal treatment (HT) for prostate cancer and to identify any possible relationship with biochemical control.Methods: Between March 1997 and November 2000, 72

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1.1.2018 · Prostate-specific antigen bounce was defined as a ≥0.2-ng/mL increase above the interval PSA nadir, followed by a decrease to nadir or below. Prostate-specific antigen relapse was defined as post-radiation therapy PSA nadir + 2 ng/mL. Median follow-up was 9.2 years (interquartile range, 6.9

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7. PSA behaviour after radiotherapy – PSA bounce. (Updated on 19th May 2006) What goes up, must come down – hopefully! SUMMARY. In the absence of hormone therapy, PSA levels decline slowly after radiotherapy and can take several years to reach a nadir or minimum.

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Median time to first bounce was 9 ± 7.0 months. Median bounce duration was 3 ± 2.3 months for the Median time to first PSA bounce after treatment was 9 months (range, 3-36 months). The duration of each bounce was on average 3 months (range, 3-12 months).

Unlike the report from Critz, in which the PSA bounce was not seen in patients treated with combined implant and EBRT after 5 years, patients treated with implant alone can experience a transient rise in PSA as long as 9 years after treatment. PSA bounce is a common phenomenon after brachytherapy and occurs at a rate of 17–31%, depending on

17.7.2009 · This phenomenon called a PSA bounce or PSA spike, occurs up to 35% of patients undergoing brachytherapy [2, 4, 6–8] and 12% to 54% of men undergoing external beam radiation therapy [9–16]. In the most papers the frequency of PSA bounce seems to be higher after brachytherapy than after EBRT.

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In one study, approximately 12% of men who underwent treatment with external beam radiation therapy were reported to have a PSA bounce about nine months after treatment, on average. Doctors aren’t sure what causes a PSA bounce, though several theories exist.

17.4.2015 · It showed a statistically significant difference in PSA velocity between PSA bounce and failure: 0.08 ng/ml/month in bounce and 0.28 ng/ml/month in PSA failure by Phoenix definition. It also showed that the doubling time was not different between PSA bounce +2 and PSA failure: 9.6 and 11.7 months, respectively .

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26.3.2012 · To evaluate predictive factors for PSA bounce after 125I permanent seed prostate brachytherapy and identify criteria that distinguish between benign bounces and biochemical relapses. Men treated with exclusive permanent 125I seed brachytherapy from November 1999, with at least a 36 months follow-up were included. Bounce was defined as an

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The median time to PSA bounce, 15 months, was shorter than the median time to PSA relapse, 37 months. Fig. 1b demonstrates the individual timing for men with either PSA bounce, PSA failure or both events. The net probability for PSA relapse after bounce is shown in Fig. 2.

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Prostate specific antigen bounce after intensity-modulated radiation therapy in an Asian population. The present study aimed to determine the prevalence and factors that predict “PSA bounce” after intensity-modulated radiation therapy By the end of 24 months, 86.9% of PSA bounce phenomenon would have occurred.

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23.6.2015 · Clinical follow-up and PSA measurements were assessed after 1.5, 3, 6, and 12 months, and annually thereafter. If PSA increased, additional follow-up visits were scheduled. Cases of PSA bounce were defined as a rise of at least 0.2 ng/ml above the initial PSA nadir with a subsequent decline to or below the initial nadir without treatment.

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They defined a bounce as a PSA rise ≥ 0.2 ng/ml but less than 2.0 ng/ml above the lowest level (nadir) it had reached thus far, followed by a decrease to as low or lower than the previous nadir. After a median follow-up of 9.2 years, they found that: 16 percent of patients had a bounce. The bounce occurred after an average (median) of 24.6

PSA bounce was unrelated to age, race, pretreatment PSA, Gleason score, clinical T stage or radiation dose. Mean time to PSA bounce was 9 months from the time of therapy. The respective 1 and 5-year biochemical disease-free survival rates were 100% and 82.1% for patients with PSA bounce and 93.9% and 57.7% for those without PSA bounce (p = 0.0001).

What to do if the PSA starts to rise after receiving radiation? Generally the PSA slowly starts declining after radiation and reaches its low point 12 – 18 months (sometime 24 months) after completing treatment. Occasional upticks or bounce are not usually important.

Until more is known, if you have had some form of radiation therapy for prostate cancer and experience a spike in your PSA level, it is wise to ask your physician whether this could be a PSA bounce. A common challenge. Rising PSA after initial treatment often comes as a shock to the person affected, but it’s actually a common problem.

I had 3 months of Lupron before IMRT and 9 months after. PSA fell to 0.02 ng/ml 2months after IMRT, then < 0.015 for 6 mos. With Lupron slowly wearing off PSA was 0.085 and then quarterly tests at 0.2 where it stayed with increasing ultrasensitive H for 20 month. However, last my last four PSAs have been 0.29, 0.50, 0.40, and 0.60.

I chatted with my radiation doc about PSA bounce today. I consider him a very good doctor that is an absolutely great guy. This is what he told me. He said post radiation PSA bounce is primarily associated with primary treatment of an intact prostate and especially associated with bracytherapy far more than external beam radiation.

6.11.2019 · PSA bounce, which is frequently observed after LDR-brachytherapy, is a curious phenomenon caused by an unknown mechanism. Reportedly, 17% to 62% of patients are diagnosed with PSA bounce using several definitions. The median time

On 9/11/2007 Xtina wrote: Hi All, My dad had the permanent radiation seeds brachytherapy done in June of this year and he went for his 3 month check up today Sept 11th 07. His PSA levels at time of diagnosis was 4.27 (gleeson 6) and now after 3 months of Brachy his PSA is down to 2. Can anyone tell

A PSA 3 months after treatment and every 3 months after that is the normal diagnostic approach until the patient reaches the anticipated nadir of treatment (below

Introduction: Prostate-specific antigen (PSA) bounce after brachytherapy has been well-documented. This phenomenon has also been identified in patients undergoing stereotactic body radiation therapy (SBRT). While the parameters that predict PSA bounce have been extensively studied in prostate brachytherapy patients, this study is the first to

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PSA jumps By Four Points In Three Weeks. I do NOT have any history whatsoever of prostate cancer on either my father’s side of the family or my mother’s side. When doctors started checking my PSA fifteen years ago it was always a fraction of one percent, like 0.05, etc.

Treated at 46. Gleason 7, PSA 9.4. Recently, my PSA started rising 24 months after I125 seed implants and 7 weeks of CBRT. PSA went down to 1.6. PSA is now 6.1. Both the urologist and radiation oncologist say to wait and see what the PSA does. We’re hoping for it to level out. This would indicate a bounce. I’m on a PSA test schedule of every

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radical treatment should have their PSA levels checked six weeks following treatment, at least every three months for the first two years and then at least once or twice a year thereafter. After at least two years, men with a stable PSA who have had no significant treatment complications should be offered follow-up outside hospital (egin primary

PSA’s can bounce around a bit which is why one test is of little value. A steady upward trend with three or more tests is of concern so your doctor is right on with his assessment. When my PSA hit 4.9 (after a steady climb from 2.8 over four years and prior to my biopsy), I ran to the internet looking for good reasons to avoid the biopsy and

28.10.2019 · Long-term outcomes were determined in patients who had remained free of disease 3 years after their initial treatment. Median follow-up was 6 years for the external-beam radiation patients and 5 years 3 months for the brachytherapy patients. No difference in any disease outcome was evident between patients with or without a PSA bounce at 10 years.

30.7.2018 · PSA measurements after BT were performed every 3 months for the first 3 years, and every 6 months thereafter. Definitions of PSA bounce. The date of BT was considered to be Day 0 of follow-up. PSA bounce was defined as an increase of ≥0.2 ng/ml above the initial PSA nadir, with a subsequent decline to or below that initial nadir without

Author: Katsumaro Kubo, Koichi Wadasaki, Tomoki Kimura, Yuji Murakami, Mitsuru Kajiwara, Jun Teishima, Akio

To your question ”How much should PSA drop after 6 months radiation seed implant?” What I do understand is that after radiation, either seeds, (brachytherapy), or external beam or cryotherapy the PSA will drop slowly, frequently reaching its nadir (low point) after several years.

PSA bounce was unrelated to age, race, pretreatment PSA, Gleason score, clinical T stage or radiation dose. Mean time to PSA bounce was 9 months from the time of therapy. The respective 1 and 5-year biochemical disease-free survival rates were 100% and 82.1% for patients with PSA bounce and 93.9% and 57.7% for those without PSA bounce (p = 0.0001).

I was diagnosed with PC in 12/07 biopsy glesson 3+4=7 pre RP PSA 8.9. post op pathology Glesson 4+3=7, negative margins, nodes and seminal vessals clear with small extraa capsular extension. PSA fell to 0.04 after 6 months but then began to rise and was 0.16 by 12/08, and SRT was recomended.

what does a .3 psa after radiation – [QUOTE=kd66;3763342] Daff – can you tell us more about the proton radiation treatments? How many did you have and did you have any side effects? How did it affect your PSA? Ken Hi Ken- Thanks for the followups you posted- sorry I didn’t respond sooner, but I’ve just

23.11.2018 · The benign PSA bounce was observed in 25 patients (35.2%) and the frequency of PSA bounce was not associated with risk groups or Gleason score. The median time to bounce was 11.0 months (range, 2.9–38.5 months) after SBRT, and the median height of PSA bounce was 0.53 ng/ml (range, 0.24–2.62 ng/ml).

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This morning, a couple of weeks after a positive and uplifting CT Scan that showed no noticeable spread of my prostate cancer, came a PSA blood test result that totally deflated me. Yep, my PSA is still very low but there’s been yet another doubling time of less than 3 months – 0.044 in April to 0.074 in July to 0.176 in Oct to today’s 0.417.

28.10.2019 · The introduction of prostate-specific antigen (PSA) as a reliable tumor marker for prostate cancer brought significant changes in the end points used for outcome reporting after therapy. With regard to a definition of failure after radiation, a consensus was reached in 1996 that took into account the particular issues of an intact prostate

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The misdiagnosis of a PSA relapse and its unnecessary therapy as well as the patient’s concern about a relapse can be avoided if the physician and patient are informed about the characteristic features of a PSA bounce. Literature: Engeler DS et al.: PSA bounce after 125 brachytherapy for prostate cancer as a favorable prognosticator.

Median time from completion of radiotherapy to first PSA bounce ranges from 9 to 35 months. [5] Median time to first PSA bounce was 17 months in the report by Naghavi et al.(95% CI: 15-18 months). PSA kinetics after prostate brachytherapy: PSA bounce phenomenon and its

The ASTRO guidelines suggest that a man should have a PSA test every three or four months during the first two years after treatment, and every six months after that. The theoretical date of failure is then backdated”to the midpoint between the PSA nadir and the first of the three consecutive rises.

PSA trend for a 46‐year‐old man with a T2a Gleason 6 adenocarcinoma of the prostate treated with permanent seed iodine‐125 prostate brachytherapy. The PSA bounce peaked at 24 months after the implant at a level of 7.5 ng/mL, but decreased spontaneously without intervention and remains undetectable at 6.5 years.

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All time intervals were calculated from the completion date of radiation therapy. PSA bounce was defined as an initial increase in serum PSA of at least 0.5 ng./ml., followed by a decrease to pre-bounce baseline serum PSA values no more than 60 months after external beam radiation therapy.

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After radiation therapy, doctors need to look for confirmation from multiple tests because PSA can “bounce” or jump up for a short period, and will later return to its low level. If only one test was performed it’s possible that it could have occurred during a bounce phase,

4.1.2010 · PSA levels in a prostate cancer patient are monitored after a patient’s treatments, and after a successful course of EBRT the levels should decline gradually over the following 18 to 24 months. A continued rise in PSA can indicate relapsing disease.

In vitro models showed that dutasteride has anti-tumor properties against human prostate cancer and—confirmed in a mice model. Perrotti et al. 48 studied 35 men with BCR after definitive treatment, 46 % had a PSA decrease >10 % and 25 % had PSA decrease >50 %. After 6 months, PSA levels decreased in 24 patients (68 %).

8.11.2006 · So what should you do if have a rise in your PSA level after radiation? ”You have to get a few readings over the next year,” Horwitz says, adding that most doctors recommend screening every three months or so. ”But try to relax and realize that it’s OK, that this happens, and that a bounce does not mean your cancer has recurred.”

8.11.2006 · So what should you do if have a rise in your PSA level after radiation? ”You have to get a few readings over the next year,” Horwitz says, adding that most doctors recommend screening every three months or so. ”But try to relax and realize that it’s OK, that this happens, and that a bounce does not mean your cancer has recurred.”

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Prostate specific antigen bounce after intensity-modulated radiation therapy in an Asian population Yu Guang Tan (29.6%) experienced “PSA bounce”, at a median time of 16 months and lasted for 12 months. Age remained the most The present study is the first to examine PSA bounce after intensity modulated radiation therapy (IMRT) in an

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then dropped to 0.11 after this surgery. Three months later PSA had risen to 0.16. He then had salvage pelvic RT 66Gy in 33 fractions at 8 months post RP. PSA dropped to 0.05 in four months but increased to 0.08 in six months later as bounce 1, dropping back to 0.05 three months later, then up to 0.07 as bounce 2 at 14 months, then down to

PSA bounce was unrelated to age, race, pretreatment PSA, Gleason score, clinical T stage or radiation dose. Mean time to PSA bounce was 9 months from the time of therapy. The respective 1 and 5-year biochemical disease-free survival rates were 100% and 82.1% for patients with PSA bounce and 93.9% and 57.7% for those without PSA bounce (p = 0.0001).

Prostate cancer patients who have a temporary rise in their prostate specific antigen (PSA) levels after radiation therapy — called a PSA bounce — are not at an increased risk of their cancer coming back any more than those who don’t have a temporary rise, according to the largest study of its kind presented November 8, 2006, at the American

Clinical follow-up and PSA measurements were assessed after 1.5, 3, 6, and 12 months, and annually thereafter. If PSA increased, additional follow-up visits were scheduled. Cases of PSA bounce were defined as a rise of at least 0.2 ng/ml above the initial PSA nadir with a subsequent decline to or below the initial nadir without treatment.

PSA is a glycoprotein produced primarily by the epithelial cells that line the acini and ducts of the prostate gland. PSA is concentrated in prostatic tissue, and serum PSA levels are normally very low.

Thus far, 16% of patients in the study developed a PSA-B after completing initial DE-EBRT at a median of 24.6 months. The study found that patients [who experienced a PSA-B] were half as likely to develop a subsequent rise in PSA with further follow-up and had a significantly lower likelihood of developing metastatic disease.

Read ”Prostate-Specific Antigen Bounce After Dose-Escalated Radiation Therapy for Prostate Cancer is an Independent Predictor for Distant Metastasis, Cancer-Specific Survival, and Overall Survival, International Journal of Radiation Oncology Biology Physics” on DeepDyve, the largest online rental service for scholarly research with thousands of

I just had my latest PSA test result and 4 months after finishing radiotherapy it’s up again. I’ve heard of PSA bounce and there’s a lot on it on the Web when it happens after having had just radiotherapy but I can find very little that talks about it after surgery and radiotherapy.

The study recommended a 2nd PSA test 4-6 weeks after the elevated result PRIOR to having a biopsy. So, that is what I did & the result was that my PSA went back down to 1.4. So, the BIG question is what do I do now? There seems to be no consensus. I decided to wait 3 months & have another PSA test along with a free PSA test.

After radiotherapy or brachytherapy, your PSA should drop to its lowest level (nadir) after 18 months to two years. Your PSA level won’t fall to zero as your healthy prostate cells will continue to produce some PSA. Your PSA level may actually rise after radiotherapy treatment, and then fall again. This is called ‘PSA bounce’.

PSA bounce was defined as a PSA increase of at least 0.4 ng/mL, followed by any PSA decrease. Biochemical failure was defined by both the American Society for Therapeutic Radiology and Oncology 1996 and 2006 consensus definitions. Results: The median follow-up was 76 months. The median length of time until the first PSA bounce was 13.6 months.

Hello. My husband 51, had a radical robotic prostatectomy 3.5 months ago. his pre surgery psa was 9.5. one month after surgery it was .18. one month later it was .14 and then one month after that it was UP to .16. So.. the surgeon is saying he would like to see it ’unreadable’ by now, and is recommending a 7 week round of radiation 5x a week.

PSA recurrence is defined by a PSA of 0.2ng/ml to 0.4ng/ml after removal of the cancerous prostate. PSA recurrence after Radiation therapy (RT) is more difficult to determine as PSA initially increase’s (known as PSA bounce) after treatment and does not reach its lowest level for up to 18 months.

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transient rise after treatment (termed ‘bounce’),9 serial measurements showing a gradual rise in PSA may mean disease is recurring or progressing At 12 months, Bob’s PSA was 7.1 ng/mL falling to 7.0 ng/mL after a further 12 months. Digital rectal examination remained nonsuspicious with no

To assess the factors effecting PSA bounce and to identify any possible relationship with biochemical control after 3-D conformal radiotherapy (3D-CRT) and total androgen deprivation (TAD) for prostate cancer by evaluating four previously described PSA bounce definitions.

Also after RT there is ‘PSA bounce.’ He states this can happen about 9 months after treatment to about 1/3 of men. He says it’s a sudden rise of 0.5 to 1 ng/mL followed by a drop back down. He quotes another authority, Dr Song, “ironically, men who develop a PSA bounce ultimately have a better disease-free survival rate than men who did

Men who had PSA relapse after salvage therapy had a median overall survival of nearly 14 years. Salvage radiation therapy (SRT) given after radical prostatectomy may improve outcomes in prostate cancer (PCa) patients, even in those who fail the treatment, according to study findings presented at the

Prostate-specific antigen (PSA) is a protein made by the cells of the prostate gland. PSA is mostly found in semen, but it is also normal to find small amounts of PSA in the blood of healthy men. A PSA test measures the amount of PSA in the blood.

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Tumour and immune cell dynamics explain the PSA bounce after prostate cancer brachytherapy Yoichiro Yamamoto*,1,2, Chetan P Offord3,{, Go Kimura 4, Shigehiko Kuribayashi5, Hayato Takeda ,

Initial PSA’s after brachytherapy were 2.8, 2.5, and 2.1. However, went up to 5.9 three months ago, and most recent PSA is 7.5. Obviously, PSA is all over the map. Will be going in this week to discuss options, but would appreciate any thoughts. PSA anxiety is working overtime.

These differences in time of PSA rise for a bounce vs. dian number of PSA values after treatment was 9 for the a bF were highly significant for all bounce definitions (p < patients who exhibited a PSA bounce of $0.2 ng/mL and 8 0.0001). for those who did not have a bounce (p < 0.0001).

PSA bounce was unrelated to age, race, pretreatment PSA, Gleason score, clinical T stage or radiation dose. Mean time to PSA bounce was 9 months from the time of therapy. The respective 1 and 5-year biochemical disease-free survival rates were 100% and 82.1% for patients with PSA bounce and 93.9% and 57.7% for those without PSA bounce (p = 0.0001).

psa levels after brachytherapy (too old to reply) annieb995 2007-02-04 22:08:43 UTC. Permalink causes the PSA to bounce up and down and it is only a long term trend upward that indicates failure. you that 1.4 PSA just 3 months after treatment is not a bad PSA. I will also tell you,

Using these criteria, men and their doctors can pinpoint the likelihood of developing metastatic disease. For example: If a man has Gleason 7 disease, has his first PSA recurrence more than two years after surgery, and has a PSA doubling time longer than 10 months, his likelihood of being, free of metastasis at seven years is 82 percent.

PROSTATE SPECIFIC ANTIGEN BOUNCE AFTER RADIOACTIVE SEED IMPLANTATION FOLLOWED BY EXTERNAL BEAM Median time to PSA bounce was 18 months from the time of implant and 92% of bounces were observed within 36 months. Median pre-bounce PSA was 0.7 ng./ml. (range 0.1 to 8.9) and median bounce height (increase above the pre -bounce level

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PSA bounce • Serum PSA levels typically fall after RT and can then rise transiently, at a median of 12 to 18 months after treatment. • PSA bounce can occur in the absence of recurrent disease and does not necessarily signify a treatment failure or constitute an indication for therapeutic intervention. • There are no definitive methods to

To clarify the significant clinicopathological and postdosimetric parameters to predict PSA bounce in patients who underwent low-dose-rate brachytherapy (LDR-brachytherapy) for prostate cancer. We studied 200 consecutive patients who received LDR-brachytherapy between July 2004 and November 2008. Of them, 137 patients did not receive

Read ”Permanent 125i Seed Prostate Brachytherapy: Early PSA Value as a Predictor of PSA Bounce Occurrence, International Journal of Radiation Oncology Biology Physics” on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at

None received adjuvant ADT. They defined a bounce as a PSA rise ≥ 0.2 ng/ml but less than 2.0 ng/ml above the lowest level (nadir) it had reached thus far, followed by a decrease to as low or lower than the previous nadir. After a median follow-up of 9.2 years, they found: 16% of patients had a bounce; The bounce occurred after a median of 24

Time to PSA rise differentiates the PSA bounce after HDR and LDR brachytherapy of prostate cancer. Wojciech Burchardt, Janusz Skowronek. J Contemp Brachytherapy 3 fractions of 10.5 or 15 Gy. The initial PSA level (iPSA) was assessed before treatment, then PSA was rated every 3 months over the first 2 years, and every 6 months during the

Brachytherapy FAQ. Search for: (PSA bounce) during this time. PSA bounce is not related to the success of the treatment but speak to your specialist nurse or doctor if you are worried about your PSA level. you should avoid close contact with pregnant women or children under the age of two for the first three months after treatment.

Median PSA follow-up was 24 months (range 18-78 months). 34 (28%) patients had a PSA bounce. The median time to PSA bounce was 9 months, and the median bounce size was 0.50ng/mL. On univariate analysis, only younger age (p = .011) was shown to be associated with an increased incidence of PSA bounce.

Patients with PSA bounce in the first few years after brachytherapy (internal radiation) are less likely to develop a recurrence and have an even better overall success rate than patients without a short-term increase in PSA.

RESULTS: A total of 114 patients treated between 2001 and 2009 were eligible for analysis. At a median followup of 66 months, the PB was found in 45 (39%) patients with a median time to bounce of 16 months (range, 3-76 months). The median time to PSA normalization after a PB was 9 months (range, 2-40 months).

Apr 28, 2016. Prostate-specific antigen (PSA) ”bounce” — a small rise and fall in PSA level after curative radiation therapy for prostate cancer — is more common in men who are more sexually active, according to a study from Japan. PSA bounce can be a worrisome event because it can be difficult to distinguish from. Jan 20, 2017.

I started this Blog after being diagnosed with Prostate Cancer in 2010. I thought I was going to die! It was a way of keeping family and friends informed but then became a campaigning tool, helping to make improvements in hospitals nationally. 9 years on, after successful surgery, my PSA is still undetectable.

Clinical follow-up and PSA measurements were assessed after 1.5, 3, 6, and 12 months, and annually thereafter. If PSA increased, additional follow-up visits were scheduled. Cases of PSA bounce were defined as a rise of at least 0.2 ng/ml above the initial PSA nadir with a subsequent decline to or below the initial nadir without treatment.

Noncancerous PSA increases, termed ”PSA Bumps” can develop after 1 to 4 years, creating consternation about the possibility of cancer recurrence. The PSA Bump is thought to result from a delayed immune reaction in the prostate. The good news is that a PSA Bump may actually be associated with higher cure rates.

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height, and duration of PSA bounce were 17 months, 0.29 ng/mL, and 7.0 months, [8,9]. We investigated PSA bounce rates after LDR-brachytherapy to elucidate independent predictors of PSA bounce in our series of patients. Methods Two hundred patients who were clinically diagnosed

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PSA bounce after (125)I-brachytherapy for prostate cancer as a favorable prognosticator Daniel Engeler,Christoph Schwab,Armin F Thöni,Werner Hochreiter,Ladislav Prikler, Stefan Suter,Patrick Stucki,Johann Schiefer,Ludwig Plasswilm,Hans-Peter Schmid & bounce was 12 months,

In the study, a PSA-B was defined as a rise in PSA of 0.2 to 2 ng/mL, followed by a drop in PSA to nadir or below initial nadir. The authors have been following the patients for a median of 9.2 years. Thus far, 16% of patients in the study developed a PSA-B after completing initial DE-EBRT at a median of 24.6 months.

However, there is a phenomenon called ”PSA bounce” in which during the first 18 months or so after radiation treatment, the PSA goes up (presumably due to radiation-induced inflammation in the prostate gland) and then later comes down. So, it is possible that the rising PSA your father is having may be due to PSA bounce.

At a median of 18 months after I-125 seed implantation, 38 men (24.7%) experienced PSA bounce, defined as a PSA rise of at least 0.4 ng/mL above an initial PSA nadir followed by a subsequent decline to or below the initial nadir without treatment. Of the 154 patients, 77 completed the IIEF-15 questionnaire 18 months after brachytherapy.

PSA and Advanced Prostate Cancer. • You experience three (3) consecutive rises in your PSA score after having reached your nadir* score. After receiving radiation treatment, it is entirely normal for some men to experience a “PSA bounce” or jump for a short period of time.

Prostate specific antigen bounce after intensity-modulated radiation therapy in an Asian population: Yu Guang Tan a, Weber Lau Kam On a, Hong Hong Huang a, Terence Tan Wee Kiat b: a Department of Urology, Singapore General Hospital, Singapore; b Department of Radiotherapy, National Cancer Centre Singapore, Singapore

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PSA bouncing after brachytherapy HDR and external beam radiation therapy: patients who exhibited a PSA bounce and did not but non-bouncer reached PSA nadir earlier than bouncer, Some patients have a temporary PSA spike, usually within 12-30 months of radiation therapy [2-4]. Most PSA bounces have magnitude of 1 ng/ml or less.

The PSA test is a blood test that can help diagnose prostate problems, including prostate cancer. Here we explain who can have a PSA test, what will happen if you have a test, and what your PSA

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